منابع مشابه
Are AgNORs useful in distinguishing follicular hyperplasia from follicular lymphoma?
Argyrophilic nucleolar organiser regions (AgNORs) in 28 follicular lymphomas and 30 lymph nodes showing reactive follicular hyperplasia were studied to see if they were helpful in distinguishing follicular lymphoma from follicular hyperplasia in paraffin wax tissue sections. Mean nuclear counts were greater in follicular hyperplasia (3.71 v 3.11). This difference was significant but counts over...
متن کاملImmunotherapy with rituximab in follicular lymphomas.
BACKGROUND Non-Hodgkin Lymphomas (NHL) represent a recent and fascinating domain of hemato-oncology, in which remarkable progress has been made. The conventional treatments of indolent lymphomas do not extend the survival rate, nor do they cure. Recent directions are centered on using several new drugs that are capable of overcoming the mechanisms that are resistant to recovery. The initiation ...
متن کاملIntensive therapies in follicular non-Hodgkin lymphomas.
At diagnosis, approximately 80% of patients with follicular lymphoma (FL) have disseminated disease with one or more extranodal localizations (Ann Arbor stage IV), mostly corresponding to bone marrow (BM) involvement. Conventional chemotherapy is not curative nor does it substantially modify the natural course of the disease. Most patients with disseminated FL ultimately die from the disease, w...
متن کاملMYC rearrangements in histologically progressed follicular lymphomas.
Histologic transformation of low-grade follicular lymphoma to an aggressive-grade lymphoma occurs in 60% to 80% of patients during their clinical course. The events that drive the transformation process are poorly understood. Deregulation of the MYC gene has been implicated in a small number of cases. This observation led us to examine the molecular organization of the MYC oncogene in 38 cases ...
متن کاملControversy I: controversies in follicular lymphomas
The last decade has resulted in significant improvement in the prognosis of patients with advanced stage follicular lymphoma. The old paradigm, that the median survival for these patients ranged from 5-7 years with no plateau in the survival curve, no longer remains valid. Fisher et al. demonstrated that sequential studies conducted by SWOG demonstrated improved survival over the past several d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1990
ISSN: 0021-9746
DOI: 10.1136/jcp.43.11.964